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Direct observation of an ensemble of stable collapsed states in the mechanical folding of ubiquitin

Statistical theories of protein folding have long predicted plausible mechanisms for reducing the vast conformational space through distinct ensembles of structures. However, these predictions have remained untested by bulk techniques, because the conformational diversity of folding molecules has be...

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Detalhes bibliográficos
Main Authors: Garcia-Manyes, Sergi, Dougan, Lorna, Badilla, Carmen L., Brujić, Jasna, Fernández, Julio M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705594/
https://ncbi.nlm.nih.gov/pubmed/19541635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901213106
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