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Single homopolypeptide chains collapse into mechanically rigid conformations
Huntington's disease is linked to the insertion of glutamine (Q) in the protein huntingtin, resulting in polyglutamine (polyQ) expansions that self-associate to form aggregates. While polyQ aggregation has been the subject of intense study, a correspondingly thorough understanding of individual...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722357/ https://ncbi.nlm.nih.gov/pubmed/19549822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900678106 |
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