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Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans

The genome of Caenorhabditis elegans possesses two genes, dpy-18 and phy-2, that encode α subunits of the enzyme prolyl 4-hydroxylase. We have generated deletions within each gene to eliminate prolyl 4-hydroxylase activity from the animal. The dpy-18 mutant has an aberrant body morphology, consisten...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Friedman, Lisa, Higgin, Joshua J., Moulder, Gary, Barstead, Robert, Raines, Ronald T., Kimble, Judith
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC18302/
https://ncbi.nlm.nih.gov/pubmed/10781079
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