Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans
The genome of Caenorhabditis elegans possesses two genes, dpy-18 and phy-2, that encode α subunits of the enzyme prolyl 4-hydroxylase. We have generated deletions within each gene to eliminate prolyl 4-hydroxylase activity from the animal. The dpy-18 mutant has an aberrant body morphology, consisten...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10781079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.9.4736 |
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