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Role of Monocyte-Acquired Hemozoin in Suppression of Macrophage Migration Inhibitory Factor in Children with Severe Malarial Anemia

Severe malarial anemia (SMA), caused by Plasmodium falciparum infections, is one of the leading causes of childhood mortality in sub-Saharan Africa. Although the molecular determinants of SMA are largely undefined, dysregulation in host-derived inflammatory mediators influences disease severity. Mac...

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Bibliographische Detailangaben
Hauptverfasser: Awandare, Gordon A., Ouma, Yamo, Ouma, Collins, Were, Tom, Otieno, Richard, Keller, Christopher C., Davenport, Gregory C., Hittner, James B., Vulule, John, Ferrell, Robert, Ong'echa, John M., Perkins, Douglas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828375/
https://ncbi.nlm.nih.gov/pubmed/17060471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01327-06
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