Cystic fibrosis CFBE41o- cells contain TLR1 SNP I602S and fail to respond to Mycobacterium abscessus

Por Kempaiah, Prakasha, Davidson, Lisa B., Perkins, Douglas J., Byrd, Thomas F.
Publicado no J Cyst Fibros (2013)

Mycobacterium abscessus Glycopeptidolipid Prevents Respiratory Epithelial TLR2 Signaling as Measured by HβD2 Gene Expression and IL-8 Release

Por Davidson, Lisa B., Nessar, Rachid, Kempaiah, Prakasha, Perkins, Douglas J., Byrd, Thomas F.
Publicado em 2011

RELATIONSHIP BETWEEN INFLAMMATORY MEDIATOR PATTERNS AND ANEMIA IN HIV-1 POSITIVE AND EXPOSED CHILDREN WITH PLASMODIUM FALCIPARUM MALARIA

Por DAVENPORT, Gregory C., HITTNER, James B., WERE, Tom, ONG'ECHA, John M., PERKINS, Douglas J.
Publicado no Am J Hematol (2012)

Identification of Inflammatory Biomarkers for Pediatric Malarial Anemia Severity Using Novel Statistical Methods

Por Ong'echa, John M., Davenport, Gregory C., Vulule, John M., Hittner, James B., Perkins, Douglas J.
Publicado em 2011

Mechanisms of erythropoiesis inhibition by malarial pigment and malaria-induced proinflammatory mediators in an in vitro model

Por Awandare, Gordon A., Kempaiah, Prakasha, Ochiel, Daniel O., Piazza, Paolo, Keller, Christopher C., Perkins, Douglas J.
Publicado no Am J Hematol (2011)

Blood Mononuclear Cell Nitric Oxide Production and Plasma Cytokine Levels in Healthy Gabonese Children with Prior Mild or Severe Malaria

Por Perkins, Douglas J., Kremsner, Peter G., Schmid, Daniela, Misukonis, Mary A., Kelly, Meghan A., Weinberg, J. Brice
Publicado em 1999

Severe Malarial Anemia: Innate Immunity and Pathogenesis

Por Perkins, Douglas J., Were, Tom, Davenport, Gregory C., Kempaiah, Prakasha, Hittner, James B., Ong'echa, John Michael
Publicado em 2011

Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a P. falciparum holoendemic transmission area of Kenya

Por Munde, Elly O., Raballah, Evans, Okeyo, Winnie A., Ong’echa, John M., Perkins, Douglas J., Ouma, Collins
Publicado no BMC Infect Dis (2017)

Elevated Nitric Oxide Production in Children with Malarial Anemia: Hemozoin-Induced Nitric Oxide Synthase Type 2 Transcripts and Nitric Oxide in Blood Mononuclear Cells

Por Keller, Christopher C., Kremsner, Peter G., Hittner, James B., Misukonis, Mary A., Weinberg, J. Brice, Perkins, Douglas J.
Publicado em 2004

Reduced Peripheral PGE(2) Biosynthesis in Plasmodium falciparum Malaria Occurs through Hemozoin-Induced Suppression of Blood Mononuclear Cell Cyclooxygenase-2 Gene Expression via a...

Por Keller, Christopher C, Hittner, James B, Nti, Benjamin K, Weinberg, J Brice, Kremsner, Peter G, Perkins, Douglas J
Publicado em 2004

Interferon (IFN)-α Activation of Human Blood Mononuclear Cells In Vitro and In Vivo for Nitric Oxide Synthase (NOS) Type 2 mRNA and Protein Expression: Possible Relationship of Ind...

Por Sharara, Ala I., Perkins, Douglas J., Misukonis, Mary A., Chan, Stanley U., Dominitz, Jason A., Weinberg, J. Brice
Publicado em 1997

Reduced Hsp70 and Glutamine in Pediatric Severe Malaria Anemia: Role of Hemozoin in Suppressing Hsp70 and NF-κB Activation

Por Kempaiah, Prakasha, Dokladny, Karol, Karim, Zachary, Raballah, Evans, Ong’echa, John M, Moseley, Pope L, Perkins, Douglas J
Publicado no Mol Med (2016)

Hematological Predictors of Increased Severe Anemia in Kenyan Children Co-infected with Plasmodium falciparum and HIV-1

Por Davenport, Gregory C., Ouma, Collins, Hittner, James B., Were, Tom, Ouma, Yamo, Ong'echa, John M., Perkins, Douglas J.
Publicado em 2010

CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia

Por Raballah, Evans, Kempaiah, Prakasha, Karim, Zachary, Orinda, George O., Otieno, Michael F., Perkins, Douglas J., Ong’echa, John Michael
Publicado no PLoS One (2017)

Hemozoin Differentially Regulates Proinflammatory Cytokine Production in Human Immunodeficiency Virus-Seropositive and -Seronegative Women with Placental Malaria

Por Moore, Julie M., Chaisavaneeyakorn, Sujittra, Perkins, Douglas J., Othoro, Caroline, Otieno, Juliana, Nahlen, Bernard L., Shi, Ya Ping, Udhayakumar, Venkatachalam
Publicado em 2004

Differential Regulation of β-Chemokines in Children with Plasmodium falciparum Malaria

Por Ochiel, Daniel O., Awandare, Gordon A., Keller, Christopher C., Hittner, James B., Kremsner, Peter G., Weinberg, J. Brice, Perkins, Douglas J.
Publicado em 2005

Suppressed Circulating Bicyclo-PGE(2) Levels and Leukocyte COX-2 Transcripts in Children Co-infected with P. falciparum Malaria and HIV-1 or Bacteremia

Por Anyona, Samuel B., Kempaiah, Prakasha, Davenport, Gregory C., Vulule, John M., Hittner, James B., Ong’echa, John M., Perkins, Douglas J.
Publicado no Biochem Biophys Res Commun (2013)

Acquisition of Hemozoin by Monocytes Down-Regulates Interleukin-12 p40 (IL-12p40) Transcripts and Circulating IL-12p70 through an IL-10-Dependent Mechanism: In Vivo and In Vitro Fi...

Por Keller, Christopher C., Yamo, Ouma, Ouma, Collins, Ong'echa, John Michael, Ounah, David, Hittner, James B., Vulule, John M., Perkins, Douglas J.
Publicado em 2006

Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya

Por Munde, Elly O., Okeyo, Winnie A., Raballah, Evans, Anyona, Samuel B., Were, Tom, Ong’echa, John M., Perkins, Douglas J., Ouma, Collins
Publicado no BMC Infect Dis (2017)

Clinical Predictors of Severe Malarial Anaemia in a Holoendemic Plasmodium falciparum Transmission Area

Por Novelli, Enrico M., Hittner, James B., Davenport, Gregory C., Ouma, Collins, Were, Tom, Obaro, Stephen, Kaplan, Sandra, Ong’echa, John M., Perkins, Douglas J.
Publicado em 2010