Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a P. falciparum holoendemic transmission area of Kenya

BACKGROUND: Improved understanding of the molecular mechanisms involved in pediatric severe malarial anemia (SMA) pathogenesis is a crucial step in the design of novel therapeutics. Identification of host genetic susceptibility factors in immune regulatory genes offers an important tool for decipher...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Infect Dis
Auteurs principaux: Munde, Elly O., Raballah, Evans, Okeyo, Winnie A., Ong’echa, John M., Perkins, Douglas J., Ouma, Collins
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397818/
https://ncbi.nlm.nih.gov/pubmed/28427357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2404-y
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