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Cystic fibrosis CFBE41o- cells contain TLR1 SNP I602S and fail to respond to Mycobacterium abscessus
BACKGROUND: Mycobacterium abscessus causes lung infection in patients with cystic fibrosis. M. abscessus stimulates the host innate immune response via TLR2 on respiratory epithelial cells. Signaling through TLR2 requires the formation of TLR2/TLR1 heterodimers on the cell surface. METHODS: The abil...
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| Publicado no: | J Cyst Fibros |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4712101/ https://ncbi.nlm.nih.gov/pubmed/23403223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2013.01.001 |
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