Pharmacokinetics, Safety, and Tolerability of Oral Posaconazole Administered in Single and Multiple Doses in Healthy Adults

The pharmacokinetics, safety, and tolerability of posaconazole, an investigational triazole antifungal, were evaluated following the administration of rising single and multiple oral doses. A total of 103 healthy adults were enrolled in two phase I trials. Each study had a double-blind, placebo-cont...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Courtney, Rachel, Pai, Sudhakar, Laughlin, Mark, Lim, Josephine, Batra, Vijay
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182636/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2788-2795.2003
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