Pharmacokinetics, Safety, and Tolerability of Oral Posaconazole Administered in Single and Multiple Doses in Healthy Adults

The pharmacokinetics, safety, and tolerability of posaconazole, an investigational triazole antifungal, were evaluated following the administration of rising single and multiple oral doses. A total of 103 healthy adults were enrolled in two phase I trials. Each study had a double-blind, placebo-cont...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Courtney, Rachel, Pai, Sudhakar, Laughlin, Mark, Lim, Josephine, Batra, Vijay
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182636/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2788-2795.2003
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