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Pharmacokinetics, Safety, and Tolerability of Oral Posaconazole Administered in Single and Multiple Doses in Healthy Adults

The pharmacokinetics, safety, and tolerability of posaconazole, an investigational triazole antifungal, were evaluated following the administration of rising single and multiple oral doses. A total of 103 healthy adults were enrolled in two phase I trials. Each study had a double-blind, placebo-cont...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphov: Courtney, Rachel, Pai, Sudhakar, Laughlin, Mark, Lim, Josephine, Batra, Vijay
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936975/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2788-2795.2003
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