Pharmacokinetics, Safety, and Tolerability of Oral Posaconazole Administered in Single and Multiple Doses in Healthy Adults

The pharmacokinetics, safety, and tolerability of posaconazole, an investigational triazole antifungal, were evaluated following the administration of rising single and multiple oral doses. A total of 103 healthy adults were enrolled in two phase I trials. Each study had a double-blind, placebo-cont...

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Hlavní autoři: Courtney, Rachel, Pai, Sudhakar, Laughlin, Mark, Lim, Josephine, Batra, Vijay
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC182636/
https://ncbi.nlm.nih.gov/pubmed/12936975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2788-2795.2003
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