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Pharmacokinetics, Safety, and Tolerability of Oral Posaconazole Administered in Single and Multiple Doses in Healthy Adults

The pharmacokinetics, safety, and tolerability of posaconazole, an investigational triazole antifungal, were evaluated following the administration of rising single and multiple oral doses. A total of 103 healthy adults were enrolled in two phase I trials. Each study had a double-blind, placebo-cont...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Courtney, Rachel, Pai, Sudhakar, Laughlin, Mark, Lim, Josephine, Batra, Vijay
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936975/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2788-2795.2003
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