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Rapid Activation of ATR by Ionizing Radiation Requires ATM and Mre11

The ataxia-telangiectasia mutated (ATM) 1 and ATM- and Rad3-related (ATR) protein kinases are crucial regulatory proteins in genotoxic stress response pathways that pause the cell cycle to permit DNA repair. Here we show that Chk1 phosphorylation in response to hydroxyurea (HU) and ultraviolet radia...

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Bibliografske podrobnosti
Main Authors: Myers, Jeremy S., Cortez, David
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1821075/
https://ncbi.nlm.nih.gov/pubmed/16431910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M513265200
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