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The Mre11 complex is required for ATM activation and the G(2)/M checkpoint
The maintenance of genome integrity requires a rapid and specific response to many types of DNA damage. The conserved and related PI3-like protein kinases, ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR), orchestrate signal transduction pathways in response to genomic insults, such as...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291825/ https://ncbi.nlm.nih.gov/pubmed/14657032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg630 |
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