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The Mre11 complex is required for ATM activation and the G(2)/M checkpoint

The maintenance of genome integrity requires a rapid and specific response to many types of DNA damage. The conserved and related PI3-like protein kinases, ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR), orchestrate signal transduction pathways in response to genomic insults, such as...

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Detalhes bibliográficos
Main Authors: Carson, Christian T., Schwartz, Rachel A., Stracker, Travis H., Lilley, Caroline E., Lee, Darwin V., Weitzman, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC291825/
https://ncbi.nlm.nih.gov/pubmed/14657032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg630
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