The Mre11 complex is required for ATM activation and the G(2)/M checkpoint
The maintenance of genome integrity requires a rapid and specific response to many types of DNA damage. The conserved and related PI3-like protein kinases, ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR), orchestrate signal transduction pathways in response to genomic insults, such as...
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| Pubblicato in: | EMBO J |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657032/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg630 |
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