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Intersectin links WNK kinases to endocytosis of ROMK1

With-no-lysine (WNK) kinases are a novel family of protein kinases characterized by an atypical placement of the catalytic lysine. Mutations of 2 family members, WNK1 and WNK4, cause pseudohypoaldosteronism type 2 (PHA2), an autosomal-dominant disease characterized by hypertension and hyperkalemia....

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Autores principales: He, Guocheng, Wang, Hao-Ran, Huang, Shao-Kuei, Huang, Chou-Long
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1821066/
https://ncbi.nlm.nih.gov/pubmed/17380208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30087
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