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Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms
WNK kinases are serine-threonine kinases with an atypical placement of the catalytic lysine. Intronic deletions with increased expression of a ubiquitous long WNK1 transcript cause pseudohypoaldosteronism type 2 (PHA II), characterized by hypertension and hyperkalemia. Here, we report that long WNK1...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360592/ https://ncbi.nlm.nih.gov/pubmed/16428287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510609103 |
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