Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent

With-no-lysine (WNK) kinases coordinate volume and potassium homeostasis by regulating renal tubular electrolyte transport. In the distal convoluted tubule (DCT), potassium imbalance causes WNK signaling complexes to concentrate into large discrete foci, which we call “WNK bodies.” Although these st...

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Publié dans:Mol Biol Cell
Auteurs principaux: Boyd-Shiwarski, Cary R., Shiwarski, Daniel J., Roy, Ankita, Namboodiri, Hima N., Nkashama, Lubika J., Xie, Jian, McClain, Kara L., Marciszyn, Allison, Kleyman, Thomas R., Tan, Roderick J., Stolz, Donna B., Puthenveedu, Manojkumar A., Huang, Chou-Long, Subramanya, Arohan R.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014176/
https://ncbi.nlm.nih.gov/pubmed/29237822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-08-0529
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