Lanean...

The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage

The tumor suppressor p53 can induce apoptosis by activating gene expression in the nucleus, or by directly permeabilizing mitochondria in the cytoplasm. It has been shown that PUMA, a downstream target of p53 and a BH3-only Bcl-2 family member, plays an essential role in apoptosis induced by both nu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Peng, Yu, Jian, Zhang, Lin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820707/
https://ncbi.nlm.nih.gov/pubmed/17360476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700020104
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!