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Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin
To maintain genome integrity, eukaryotic cells initiate DNA replication once per cell cycle after assembling prereplicative complexes (preRCs) on chromatin at the end of mitosis and during G1. In S phase, preRCs are disassembled, precluding initiation of another round of replication. Cdt1 is a key m...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1817642/ https://ncbi.nlm.nih.gov/pubmed/17318181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601597 |
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