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Cell Cycle-dependent Subcellular Translocation of the Human DNA Licensing Inhibitor Geminin

Once per cell cycle replication is crucial for maintaining genome integrity. Geminin interacts with the licensing factor Cdt1 to prevent untimely replication and is controlled by APC/C-dependent cell cycle specific proteolysis during mitosis and in G(1). We show here that human geminin, when express...

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Detalhes bibliográficos
Main Authors: Dimaki, Maria, Xouri, Georgia, Symeonidou, Ioanna-Eleni, Sirinian, Chaido, Nishitani, Hideo, Taraviras, Stavros, Lygerou, Zoi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745341/
https://ncbi.nlm.nih.gov/pubmed/23814078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.453092
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