Caricamento...

Nitric Oxide Impairs Normoxic Degradation of HIF-1α by Inhibition of Prolyl Hydroxylases

Hypoxia inducible factor-1 (HIF-1) is the master regulator of metabolic adaptation to hypoxia. It is appreciated that HIF-1α accumulation is achieved under normoxic conditions by e.g., nitric oxide. We determined molecular mechanisms of HIF-1α accumulation under the impact of S-nitrosoglutathione (G...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Metzen, Eric, Zhou, Jie, Jelkmann, Wolfgang, Fandrey, Joachim, Brüne, Bernhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2003
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC181582/
https://ncbi.nlm.nih.gov/pubmed/12925778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-12-0791
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !