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SUPPRESSION OF HIF-1α TRANSCRIPTIONAL ACTIVITY BY THE HIF PROLYL HYDROXYLASE EGLN1

The cellular response to hypoxia is, at least in part, mediated by the transcriptional regulation of hypoxia-responsive genes involved in balancing the intracellular ATP production and consumption. Recent evidence suggests that the transcription factor, HIF-1α, functions as a master regulator of oxy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: To, Kenneth K. W., Huang, L. Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307502/
https://ncbi.nlm.nih.gov/pubmed/16157596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M504342200
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