Impaired angiogenesis in aminopeptidase N-null mice

Aminopeptidase N (APN, CD13; EC 3.4.11.2) is a transmembrane metalloprotease with several functions, depending on the cell type and tissue environment. In tumor vasculature, APN is overexpressed in the endothelium and promotes angiogenesis. However, there have been no reports of in vivo inactivation...

Full description

Saved in:
Bibliographic Details
Main Authors: Rangel, Roberto, Sun, Yan, Guzman-Rojas, Liliana, Ozawa, Michael G., Sun, Jessica, Giordano, Ricardo J., Van Pelt, Carolyn S., Tinkey, Peggy T., Behringer, Richard R., Sidman, Richard L., Arap, Wadih, Pasqualini, Renata
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815469/
https://ncbi.nlm.nih.gov/pubmed/17360568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611653104
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items