Impaired angiogenesis in aminopeptidase N-null mice

Aminopeptidase N (APN, CD13; EC 3.4.11.2) is a transmembrane metalloprotease with several functions, depending on the cell type and tissue environment. In tumor vasculature, APN is overexpressed in the endothelium and promotes angiogenesis. However, there have been no reports of in vivo inactivation...

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Detalhes bibliográficos
Main Authors: Rangel, Roberto, Sun, Yan, Guzman-Rojas, Liliana, Ozawa, Michael G., Sun, Jessica, Giordano, Ricardo J., Van Pelt, Carolyn S., Tinkey, Peggy T., Behringer, Richard R., Sidman, Richard L., Arap, Wadih, Pasqualini, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815469/
https://ncbi.nlm.nih.gov/pubmed/17360568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611653104
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