Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment

Processes that promote cancer progression such as angiogenesis require a functional interplay between malignant and nonmalignant cells in the tumor microenvironment. The metalloprotease aminopeptidase N (APN; CD13) is often overexpressed in tumor cells and has been implicated in angiogenesis and can...

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Autori principali: Guzman-Rojas, Liliana, Rangel, Roberto, Salameh, Ahmad, Edwards, Julianna K., Dondossola, Eleonora, Kim, Yun-Gon, Saghatelian, Alan, Giordano, Ricardo J., Kolonin, Mikhail G., Staquicini, Fernanda I., Koivunen, Erkki, Sidman, Richard L., Arap, Wadih, Pasqualini, Renata
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277167/
https://ncbi.nlm.nih.gov/pubmed/22307623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120790109
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