An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment

Mammalian cell membranes provide an interface between the intracellular and extracellular compartments. It is currently thought that cytoplasmic signaling adapter proteins play no functional role within the extracellular tumor environment. Here, by selecting combinatorial random peptide libraries in...

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Detalhes bibliográficos
Main Authors: Mintz, Paul J., Cardó-Vila, Marina, Ozawa, Michael G., Hajitou, Amin, Rangel, Roberto, Guzman-Rojas, Liliana, Christianson, Dawn R., Arap, Marco A., Giordano, Ricardo J., Souza, Glauco R., Easley, Jeffrey, Salameh, Ahmad, Oliviero, Salvatore, Brentani, Ricardo R., Koivunen, Erkki, Arap, Wadih, Pasqualini, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630201/
https://ncbi.nlm.nih.gov/pubmed/19168626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807543105
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