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An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment

Mammalian cell membranes provide an interface between the intracellular and extracellular compartments. It is currently thought that cytoplasmic signaling adapter proteins play no functional role within the extracellular tumor environment. Here, by selecting combinatorial random peptide libraries in...

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Autors principals: Mintz, Paul J., Cardó-Vila, Marina, Ozawa, Michael G., Hajitou, Amin, Rangel, Roberto, Guzman-Rojas, Liliana, Christianson, Dawn R., Arap, Marco A., Giordano, Ricardo J., Souza, Glauco R., Easley, Jeffrey, Salameh, Ahmad, Oliviero, Salvatore, Brentani, Ricardo R., Koivunen, Erkki, Arap, Wadih, Pasqualini, Renata
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630201/
https://ncbi.nlm.nih.gov/pubmed/19168626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807543105
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