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From combinatorial peptide selection to drug prototype (II): Targeting the epidermal growth factor receptor pathway
The epidermal growth factor receptor (EGFR), a tyrosine kinase, is central to human tumorigenesis. Typically, three classes of drugs inhibit tyrosine kinase pathways: blocking antibodies, small kinase inhibitors, and soluble ligand receptor traps/decoys. Only the first two types of EGFR-binding inhi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841862/ https://ncbi.nlm.nih.gov/pubmed/20190183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915146107 |
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