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The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain
Nerve growth factor (NGF) is involved in pain transduction mechanisms and plays a key role in many persistent pain states, notably those associated with inflammation. On this basis, both the NGF ligand and its receptor TrkA (tyrosine kinase A) represent an eligible target for pain therapy. Although...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815293/ https://ncbi.nlm.nih.gov/pubmed/17301229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611253104 |
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