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The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain

Nerve growth factor (NGF) is involved in pain transduction mechanisms and plays a key role in many persistent pain states, notably those associated with inflammation. On this basis, both the NGF ligand and its receptor TrkA (tyrosine kinase A) represent an eligible target for pain therapy. Although...

詳細記述

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書誌詳細
主要な著者: Ugolini, Gabriele, Marinelli, Sara, Covaceuszach, Sonia, Cattaneo, Antonino, Pavone, Flaminia
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815293/
https://ncbi.nlm.nih.gov/pubmed/17301229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611253104
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