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Molecular Dynamics Simulations of the NGF-TrkA Domain 5 Complex and Comparison with Biological Data

The nerve growth factor (NGF) is an important pharmacological target for Alzheimer's and other neurodegenerative diseases. Its action derives partly from its binding to the tyrosine kinase A receptor (TrkA). Here we study energetics and dynamics of the NGF-TrkA complex by carrying out multinano...

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Detalhes bibliográficos
Main Authors: Settanni, Giovanni, Cattaneo, Antonino, Carloni, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302795/
https://ncbi.nlm.nih.gov/pubmed/12668437
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