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Characterization of an NGF–P-TrkA Retrograde-Signaling Complex and Age-Dependent Regulation of TrkA Phosphorylation in Sympathetic Neurons

Nerve growth factor (NGF) is a target-derived trophic factor for developing sympathetic and cutaneous sensory neurons. NGF promotes growth and survival of neurons via activation of the receptor tyrosine kinase TrkA. We used compartmentalized cultures of sympathetic neurons to address the mechanism o...

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Pubblicato in:J Neurosci
Autori principali: Tsui-Pierchala, Brian A., Ginty, David D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783056/
https://ncbi.nlm.nih.gov/pubmed/10493722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-19-08207.1999
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