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Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival
NGF and NT3 collaborate to support development of sympathetic neurons. Although both neurotrophins activate TrkA-dependent axonal extension, NGF is unique in its ability to promote retrograde transport of TrkA endosomes and retrograde survival. Here, we report that actin depolymerization is essentia...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262169/ https://ncbi.nlm.nih.gov/pubmed/21816277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.008 |
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