Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival

NGF and NT3 collaborate to support development of sympathetic neurons. Although both neurotrophins activate TrkA-dependent axonal extension, NGF is unique in its ability to promote retrograde transport of TrkA endosomes and retrograde survival. Here, we report that actin depolymerization is essentia...

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Hlavní autoři: Harrington, Anthony W., Hillaire, Coryse St., Zweifel, Larry S., Glebova, Natalia O., Philippidou, Polyxeni, Halegoua, Simon, Ginty, David D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262169/
https://ncbi.nlm.nih.gov/pubmed/21816277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.008
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