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Trk retrograde signaling requires persistent, Pincher-directed endosomes

Target-derived neurotrophins use retrogradely transported Trk-signaling endosomes to promote survival and neuronal phenotype at the soma. Despite their critical role in neurotrophin signaling, the nature and molecular composition of these endosomes remain largely unknown, the result of an inability...

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Auteurs principaux: Philippidou, Polyxeni, Valdez, Gregorio, Akmentin, Wendy, Bowers, William J., Federoff, Howard J., Halegoua, Simon
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021064/
https://ncbi.nlm.nih.gov/pubmed/21187387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015981108
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