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Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling
Nogo-A is one of the most potent myelin-associated inhibitors for axonal growth, regeneration, and plasticity in the adult central nervous system. The Nogo-A–specific fragment NogoΔ20 induces growth cone collapse, and inhibits neurite outgrowth and cell spreading by activating RhoA. Here, we show th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812518/ https://ncbi.nlm.nih.gov/pubmed/20083601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906089 |
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