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Trk retrograde signaling requires persistent, Pincher-directed endosomes

Target-derived neurotrophins use retrogradely transported Trk-signaling endosomes to promote survival and neuronal phenotype at the soma. Despite their critical role in neurotrophin signaling, the nature and molecular composition of these endosomes remain largely unknown, the result of an inability...

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Detalhes bibliográficos
Main Authors: Philippidou, Polyxeni, Valdez, Gregorio, Akmentin, Wendy, Bowers, William J., Federoff, Howard J., Halegoua, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021064/
https://ncbi.nlm.nih.gov/pubmed/21187387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015981108
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