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Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468

PC-cell derived growth factor (PCDGF) is an 88-kDa growth factor originally purified from the highly tumorigenic teratoma PC cell line and corresponds to the epithelin/granulin precursor. In teratoma cells, PCDGF expression was shown to be essential for tumorigenicity. We have reported that PCDGF wa...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Lu, Runqing, Serrero, Ginette
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18130/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10760271/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.8.3993
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