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Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor)

PC-cell-derived growth factor (PCDGF) is an 88-kDa glycoprotein corresponding to the granulin precursor. We have reported that PCDGF was expressed in human breast cancer cells. In estrogen-receptor positive cells, 17-β-estradiol (E(2)) transcriptionally stimulated PCDGF expression in a dose- and tim...

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Detalhes bibliográficos
Main Authors: Lu, Runqing, Serrero, Ginette
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14558/
https://ncbi.nlm.nih.gov/pubmed/11134521
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