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Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor)

PC-cell-derived growth factor (PCDGF) is an 88-kDa glycoprotein corresponding to the granulin precursor. We have reported that PCDGF was expressed in human breast cancer cells. In estrogen-receptor positive cells, 17-β-estradiol (E(2)) transcriptionally stimulated PCDGF expression in a dose- and tim...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lu, Runqing, Serrero, Ginette
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2000
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14558/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134521/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.011525198
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