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Inhibition of PC cell-derived growth factor (PCDGF)/granulin-epithelin precursor (GEP) decreased cell proliferation and invasion through downregulation of cyclin D and CDK 4 and inactivation of MMP-2

<p>Abstract</p> <p>Background</p> <p>PC cell-derived growth factor (PCDGF), also called epithelin/granulin precursor (GEP), is an 88-kDa secreted glycoprotein with the ability to stimulate cell proliferation in an autocrine fashion. In addition, some studies indicated that PCDGF participated in inva...

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Váldodahkkit: Zhou Jianfeng, Wang Shixuan, Wu Mingfu, Han Zhiqiang, Chen Gang, Wang Beibei, Tian Xun, Wang Wei, Liao Guoning, Xi Ling, Liu Yulan, Xu Gang, Lu Yunping, Ma Ding
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2007-01-01
Ráidu:BMC Cancer
Liŋkkat:http://www.biomedcentral.com/1471-2407/7/22
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