Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway

Abstract Background Granulin epithelin precursor (GEP) is reported to function as a growth factor stimulating proliferation and migration, and conferring chemoresistance in many cancer types. However, the expression and functional roles of GEP in colorectal cancer (CRC) remain elusive. The aim of th...

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Bibliografski detalji

Glavni autori:	Yi Pan, Siu Tim Cheung, Joanna Hung Man Tong, Ka Yee Tin, Wei Kang, Raymond Wai Ming Lung, Feng Wu, Hui Li, Simon Siu Man Ng, Tony Wing Chung Mak, Ka Fai To, Anthony Wing Hung Chan
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2018-06-01
Serija:	Journal of Translational Medicine
Teme:	Colorectal cancer GEP Oncogene MAPK/ERK pathway
Online pristup:	http://link.springer.com/article/10.1186/s12967-018-1530-7
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