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Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468

PC-cell derived growth factor (PCDGF) is an 88-kDa growth factor originally purified from the highly tumorigenic teratoma PC cell line and corresponds to the epithelin/granulin precursor. In teratoma cells, PCDGF expression was shown to be essential for tumorigenicity. We have reported that PCDGF wa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lu, Runqing, Serrero, Ginette
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18130/
https://ncbi.nlm.nih.gov/pubmed/10760271
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