Sterol regulation of human fatty acid synthase promoter I requires nuclear factor-Y- and Sp-1-binding sites
To understand cholesterol-mediated regulation of human fatty acid synthase promoter I, we tested various 5′-deletion constructs of promoter I-luciferase reporter gene constructs in HepG2 cells. The reporter gene constructs that contained only the Sp-1-binding site (nucleotides −82 to −74) and the tw...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18122/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10759542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040574197 |
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