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Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors

A new bicyclic template has been developed for the synthesis of peptide mimetics. Straightforward synthetic steps, starting from amino acids, allow the facile construction of a wide range of analogs. This system was designed to target the melanocortin receptors (MCRs), with functional group selectio...

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Detalhes bibliográficos
Main Authors: Cain, James P., Mayorov, Alexander V., Cai, Minying, Wang, Hui, Tan, Bahar, Chandler, Kevin, Lee, YeonSun, Petrov, Ravil R., Trivedi, Dev, Hruby, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810397/
https://ncbi.nlm.nih.gov/pubmed/16931008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.07.015
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