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Design and Microwave-Assisted Synthesis of Novel Macrocyclic Peptides Active at Melanocortin Receptors: Discovery of Potent and Selective hMC5R Receptor Antagonists

Differentiation of the physiological role of the melanocortin receptor 5 MC5R from that of other melanocortin receptors will require development of high affinity and selective antagonists. To date, a few synthetic antagonist ligands active at hMC5 receptor are available, but most do not have appreci...

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Detaylı Bibliyografya
Asıl Yazarlar: Grieco, Paolo, Cai, Minying, Liu, Lu, Mayorov, Alexander, Chandler, Kevin, Trivedi, Dev, Lin, Guangxin, Campiglia, Pietro, Novellino, Ettore, Hruby, Victor J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756086/
https://ncbi.nlm.nih.gov/pubmed/18412316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm701181n
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