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Structure–activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position
Cyclic melanotropin peptides, designed with an aromatic amino acid substitution at the N-terminal position of the MT-II-type scaffold, were prepared by solid-phase peptide synthesis and evaluated for their ability to bind to and activate human melanocortin-1, -3, -4, and -5 receptors. The structure–...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1483901/ https://ncbi.nlm.nih.gov/pubmed/16303211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2005.01.032 |
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