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Structure–activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position

Cyclic melanotropin peptides, designed with an aromatic amino acid substitution at the N-terminal position of the MT-II-type scaffold, were prepared by solid-phase peptide synthesis and evaluated for their ability to bind to and activate human melanocortin-1, -3, -4, and -5 receptors. The structure–...

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Bibliografiske detaljer
Main Authors: Grieco, Paolo, Cai, Minying, Mayorov, Alexander V., Trivedi, Dev, Hruby, Victor J.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483901/
https://ncbi.nlm.nih.gov/pubmed/16303211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2005.01.032
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