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Insight into antibody responses induced by plasmid or adenoviral vectors encoding thyroid peroxidase, a major thyroid autoantigen

Plasmid and adenoviral vectors have been used to generate antibodies in mice that resemble human autoantibodies to the thyrotrophin receptor. No such studies, however, have been performed for thyroid peroxidase (TPO), the major autoantigen in human thyroiditis. We constructed plasmid and adenovirus...

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Autori principali: GUO, J, PICHURIN, P, NAGAYAMA, Y, RAPOPORT, B, MCLACHLAN, S M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808732/
https://ncbi.nlm.nih.gov/pubmed/12780686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02170.x
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