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The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim

Graves disease, a common organ-specific autoimmune disease affecting humans, differs from all other autoimmune diseases in being associated with target organ hyperfunction rather than organ damage. Clinical thyrotoxicosis is directly caused by autoantibodies that activate the thyrotropin receptor (T...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Chen, Chun-Rong, Pichurin, Pavel, Nagayama, Yuji, Latrofa, Francesco, Rapoport, Basil, McLachlan, Sandra M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161420/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12813025/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17069
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