The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim

Graves disease, a common organ-specific autoimmune disease affecting humans, differs from all other autoimmune diseases in being associated with target organ hyperfunction rather than organ damage. Clinical thyrotoxicosis is directly caused by autoantibodies that activate the thyrotropin receptor (T...

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Hlavní autoři: Chen, Chun-Rong, Pichurin, Pavel, Nagayama, Yuji, Latrofa, Francesco, Rapoport, Basil, McLachlan, Sandra M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC161420/
https://ncbi.nlm.nih.gov/pubmed/12813025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317069
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