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The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim

Graves disease, a common organ-specific autoimmune disease affecting humans, differs from all other autoimmune diseases in being associated with target organ hyperfunction rather than organ damage. Clinical thyrotoxicosis is directly caused by autoantibodies that activate the thyrotropin receptor (T...

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書誌詳細
出版年:J Clin Invest
主要な著者: Chen, Chun-Rong, Pichurin, Pavel, Nagayama, Yuji, Latrofa, Francesco, Rapoport, Basil, McLachlan, Sandra M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161420/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12813025/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17069
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