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The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter

Pax6 transcription is under the control of two main promoters (P0 and P1), and these are autoregulated by Pax6. Additionally, Pax6 expression is under the control of the TGFβ superfamily, although the precise mechanisms of such regulation are not understood. The effect of TGFβ on Pax6 expression was...

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Detalhes bibliográficos
Main Authors: Grocott, Timothy, Frost, Victoria, Maillard, Marjorie, Johansen, Terje, Wheeler, Grant N., Dawes, Lucy J., Wormstone, I. Michael, Chantry, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1807973/
https://ncbi.nlm.nih.gov/pubmed/17251190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1105
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